CLARIS
HCC case investigation

Clinical insight that shows its work.

CLARIS brings patient state, imaging context, evidence retrieval, and validation into one transparent workstation for liver cancer research and clinician review.

61
backend tests
10
golden cases
100%
supported claims
12/12
adversarial pass
Clinician reviewing structured case information

Live Case

HCC_015

Review
Patient case builtcomplete
Imaging measurementsavailable
AFP contextobserved
Previous comparisonlimited
Triphasic HCC CT reference

Imaging context, not guesswork.

The interface distinguishes observed measurements, unavailable scans, and review flags.

Liver
Liver
CT
CT
Lung model
Lung model
How it works

A case investigation workflow, not a black-box answer.

CLARIS shows the path from patient state to assessment. The user can inspect what was used, what was skipped, and why the system stopped.

Patient case

Normalize patient, imaging, treatment, follow-up, and missing-data state.

Investigation

Route the case through clinical, imaging, longitudinal, and evidence capabilities.

Traceable synthesis

Generate a clinician-review assessment with claim-level provenance.

Agentic runtime

The agent is the investigation loop, not a decorative chatbot.

CLARIS uses an explicit state/action/observation loop so the UI can show why each module ran and when the investigation had enough evidence to stop.

1
Goal
2
State
3
Tool
4
Observation
5
Decision

Adaptive route

The case state determines whether CLARIS needs clinical context, imaging execution, treatment context, or evidence retrieval.

State memory

Every observation becomes structured state before another decision is made.

Tool trace

Each tool call is visible as part of the investigation path.

Source boundary

Claims can point to patient data, measurements, evidence, or validation findings.

Clinical modules

Specialized tools, coordinated through an inspectable runtime.

The medical logic stays deterministic where it should. Routing, state, provenance, and investigation sequencing are what become agentic.

Imaging Investigation visual

Imaging Investigation

Tracks scan availability, segmentation artifacts, measurement quality, and review flags.

Clinical Context visual

Clinical Context

Preserves AFP, treatment labels, classifications, and unavailable liver-function fields.

Evidence Review visual

Evidence Review

Retrieves only from the controlled corpus and keeps source IDs visible.

Evidence provenance

Every important statement needs a source.

The current system uses a controlled evidence corpus and deterministic trace checks. It does not pretend a missing lab, scan, or rule output exists.

Claim Trace
Current lesion measurement is available
ImagingExecutionResult
observed
TACE treatment context exists
PatientCase.treatment_history
observed
Longitudinal response cannot be established
TreatmentResponseContext
limited
Full liver-function assessment is incomplete
ClinicalContext.missing
missing
CLARISReview Required
Patient
HCC_015
TACE context
AFP observed
Assessment
Current lesion measured
Prior comparison limited
Evidence linked
Activity
Clinical
Imaging
Evidence
Workstation preview

Built for review, not blind trust.

The dashboard exposes case state, investigation activity, missing data, review flags, evidence basis, and final synthesis in one dense clinical workspace.

Open Dashboard
Research prototype

Measured on traceability, missing-data honesty, and trajectory behavior.

The current metrics are software robustness metrics from controlled fixtures. They are not clinical validation.

61
backend tests
10
golden cases
100%
supported claims
12/12
adversarial pass

Clinician-review only

Open the workstation and inspect the case state.

Launch CLARIS